How can genomics power personalized medicine through pathology?
pathologist, Dubai, UAE
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Perry J. PICKHARDT explains that as an abdominal imager he has always been focused on reading CT scans for specific clinical reasons. For instance, when examining a breast cancer patient, he looks for signs of metastatic disease or treatment response. However, CT scans provide a wealth of information beyond these immediate clinical questions.
Consider the vast amount of data present – fat, muscle, calcium deposits, and the structure of organs like the liver. While we typically don’t utilize all this information during routine screenings, it holds significant potential for understanding a patient’s overall health and risk factors. Traditionally, extracting these measures involved manual tracing and analysis, a time-consuming process.
The advent of AI has revolutionized this field by enabling automatic extraction and combination of these various body composition measures. Perry J. PICKHARDT current research focuses on leveraging AI to determine a patient’s biological age, a concept that goes beyond chronological age. Imagine knowing if someone who is 50 years old chronologically is actually biologically closer to 30 or 70.
This “biological age” holds immense prognostic power and could provide a more accurate picture of an individual’s health status and future risks compared to their chronological age alone. By combining AI with CT scan data, we can unlock valuable insights into patient health and potentially revolutionize personalized medicine.
Text generated by AI based on an exclusive interview, revised and reviewed by
Isabelle THOMASSIN
Radiologue, Paris, France
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