Focus

From de-escalation in Surgery to the latest advances in medical oncology

Breast cancer management is a broad and constantly evolving field. Whatever your specialty, the only way to improve your skills is to get out of our comfort zone and take a good look at what the other specialist are developing. Enjoy this new focus as we work on the next BCU program: Promoting Women's Health through a Multidisciplinary Approach in Breast Cancer.

Surgical Techniques and Innovations in Early Stage Breast Cancer

Breast cancer surgery has evolved in recent years thanks to technical advances such as preoperative SBRT (Stereotaxic Body Radiation Therapy) and molecular profiling enable precise, personalized treatments. Rita SAKR discuss current guidelines emphasizing de-escalation to avoid unnecessary ALND (Axillary Lymph Node dissection) and contralateral prophylactic mastectomy to reduce morbidity and improve patient quality of life.

Predictive Models for Treatment Response and Toxicities

Medicine is based on science, and the targets and predictive tools we use now and in the future are based on scientific advances. Joseph GLIGOROV guides us through the complexities of breast cancer treatment with a historical and comprehensive perspective.

HER2 + Targeted Therapies: Beyond Monoclonal Antibody

Hassan GHAZAL discusses an important issue in the treatment of HER2-positive metastatic breast cancer. He explains whether the frontline standard of care will shift from the CLEOPATRA regimen to T-DXd, depending on the results of the ongoing phase 3 DESTINY-Breast09 trial. This regimen combines pertuzumab with trastuzumab and chemotherapy, and typically involves 4 to 6 months of chemotherapy followed by maintenance with HER2-targeted therapy alone.

PAST FOCUS: State of cancer care in UAE in 2024

Prof Al SHAMSI discuss with us the results of the UAE National cancer registry and brings insights on the breast screening strategy in UAE. His presentation gives a complete view of the state of cancer care in AUE particularly through the actions of the Emirates Oncology Society.

Welcome to

breastcancerupdate.org

Free access to:

  • Live Event: February 2 to 5
  • Resources (Sessions & Expert Opinions)
  • Newsletter

Breast cancer dynamics: Molecular signature, Radiotherapy and Nuclear Medicine

It's summertime, and we're about to take you on an exciting journey through the latest advances in breast cancer treatment in a truly multidisciplinary way. We hope you'll enjoy the ride. Stay tuned and have a safe trip!

Decoding biomarkers for more personalized care

Biomarkers in breast cancer management serves as crucial indicators for diagnosis, prognosis and treatment response. They can identify patients who are likely to benefit from specific therapies and monitor treatment efficacy. Advances in biomarkers research through next-generation sequencing are improving precision medicine. Simon NAYLER tells us how this is enabling tailored treatment strategies to improve patient outcomes. We invite you to go deeper in the session section.

Molecular Imaging: at the forefront of innovation

Molecular imaging, such as positron emission tomography (PET), is increasingly used as biomarker to predict and assess treatment response in breast cancer.  Willy VANGU explain the potential prognostic value of dual biomarkers in ER positive breast cancer patients. To ensure effective patient care, potential responders to HER-targeted therapy need to be identified. Radionuclide molecular imaging can be a key asset for the detection of overexpression of EGFR (Epidermal Growth Factor Receptor) family members. To complete this interview, you can enjoy the talk of Eric ZERBIB on preoperative assessment with FDG PET Scan in the Session section.

Radiotherapy in early breast cancer

The significance of radiation therapy following neoadjuvant systemic therapy is a topic of ongoing discussion, specifically concerning regional nodal irradiation in patients achieving a complete response. We invite you to go further with Yazid BELKACEMI our next BCU Co-president. He will discuss the number of fractions for delivering a radiation therapy boost which is a critical aspect from a technical perspective, especially when using simultaneous integrated boost and the shift towards moderate hypofractionation. You’ll be able to go further with a comprehensive presentation on ongoing trials in early breast cancer by Sithembile NGIDI in the session section.

Dr Jean-Philippe MINART, BCU Chief Editor, Cannes, France