She practices both medical and radiation oncology. Sithembile trained in Clinical and Radiation Oncology at Inkosi Albert Luthuli Central Hospital and Addington Hospital and was awarded her fellowship by the College of Radiation Oncologists (CMSA). She received the MECs award of recognition and excellence when she became KwaZulu-Natal’s first female black oncologist. She currently is in private practice in Johannesburg and recently became a peer review panelist for the South African Oncology Consortium.